2006Journal of Shandong UniversityRequires access

Epilepsy induced by cerebral arteriovenous malformations:angioarchitectural characteristics and embolization treatment

Lei Han

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Abstract

Objective:To explore the size,location and feeding artery of arteriovenous malformations(AVM) by DSA and the response of embolization of AVM for epilepsy.Methods: DSA was performed in 95 patients with cerebral AVM and endovascular treatment with NBCA or ONYX was performed in all;chi-square test was used to analyze the results.Results: There was a significant association between the seizure induced by cerebral AVM and the size and the location of AVM(all P0.01),but no significant association between the number of feeding artery and the seizure((P)(0.05));of the 43 patients(43/95,45%) were found seizures,20 had their symptoms disappeared after embolization,11 had their symptoms relieved;the response rate was 72.1%.Conclusion: The bigger the AVM is and the more close the AVM is to the brain cortex,the more the patient are inclined to tempt seizure.The number of feeding artery has no relation with the epilepsy;and epilepsy has been greatly improved through endovascular embolization treatment for epileptogenic AVMs.

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Objective:To explore the size,location and feeding artery of arteriovenous malformations(AVM) by DSA and the response of embolization of AVM for epilepsy.Methods: DSA was performed in 95 patients with cerebral AVM and endovascular treatment with NBCA or ONYX was performed in all;chi-square test was used to analyze the results.Results: There was a significant association between the seizure induced by cerebral AVM and the size and the location of AVM(all P0.01),but no significant association between the number of feeding artery and the seizure((P)(0.05));of the 43 patients(43/95,45%) were found seizures,20 had their symptoms disappeared after embolization,11 had their symptoms relieved;the response rate was 72.1%.Conclusion: The bigger the AVM is and the more close the AVM is to the brain cortex,the more the patient are inclined to tempt seizure.The number of feeding artery has no relation with the epilepsy;and epilepsy has been greatly improved through endovascular embolization treatment for epileptogenic AVMs.

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Available abstract

Objective:To explore the size,location and feeding artery of arteriovenous malformations(AVM) by DSA and the response of embolization of AVM for epilepsy.Methods: DSA was performed in 95 patients with cerebral AVM and endovascular treatment with NBCA or ONYX was performed in all;chi-square test was used to analyze the results.Results: There was a significant association between the seizure induced by cerebral AVM and the size and the location of AVM(all P0.01),but no significant association between the number of feeding artery and the seizure((P)(0.05));of the 43 patients(43/95,45%) were found seizures,20 had their symptoms disappeared after embolization,11 had their symptoms relieved;the response rate was 72.1%.Conclusion: The bigger the AVM is and the more close the AVM is to the brain cortex,the more the patient are inclined to tempt seizure.The number of feeding artery has no relation with the epilepsy;and epilepsy has been greatly improved through endovascular embolization treatment for epileptogenic AVMs.

Key concepts: Embolization, Medicine, Epilepsy, Intracranial Arteriovenous Malformations, Arteriovenous malformation, Radiology, Cerebral angiography, Angiography

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