Study on relationship between angioarchitectural factors of cerebral arteriovenous malformations and epilepsy and the effect of embolization treatment

Objective To explore the relationship between angioarchitectures of cerebral arteriovenous malformations(AVM)(the size,location and feeding artery of AVM)and epilepsy and the effect of endovascular embolization treatment.Methods 95 patients had underwent aortocranial angiography by digital subtraction angiography.Seizure ratios were compared in the patients with different size,location and number of feeding artery of AVM.The AVMs were occluded with NBCA or ONYX.Results Seizure ratios of the patients with 3～6 cm AVMs(52.5%),6 cm AVMs(57.1%)were much higher than that with 3 cm AVMs(0)(all P0.01).Seizure ratio of the patients with the AVMs located at brain cortex was much higher than those with the AVMs located at basal ganglia or posterior cranial fossa(all P0.01),but there was no significant difference in seizure ratio between the different number of feeding artery(all P0.05).Seizure was found in forty-three patients.After embolization the seizure in 20 patients disappeared,11 patients had been improved greatly.The total effective power was 72.1%.Conclusions The size and location of AVM is significantly associated with the onset of seizure.The number of feeding artery has no relation with the seizure.Endovascular embolization for the AVMs has got better cure effect.