Therapeutic Effect of Zinc in the Prevention and Treatment of Children Rotavirus Enteritis

Objective To investigate the therapeutic effect of oral zinc supplementation in children rotavirus enteritis. Methods 150 cases of rotavirus enteritis of sick children from 6 to 24 months were randomly divided into two groups.The intervention group had 75 cases and the control group had 75 cases.Both groups were given the same conventional treatment and the intervention group was given additional Zinc Gluconate.The clinical therapeutic effect of the two groups was observed and the diarrhea rate and severity of the two groups after treatment were observed through one time follow up in the first,second and the third month after treatment. Results In intervention group,54 cases showed significant effect,17 cases showed effect,4 cases showed no effect,and the general effect rate was 94.67%;in control group,41 cases showed significant effect,15 cases showed effect,19 cases showed no effect and the general effect rate was 74.67%.The difference of the therapeutic effect between the two groups was statistically significant(P0.05).The diarrhea rate of the two groups in the following up the first,second and third month after treatment showed statistically significant difference(P0.05).The severe diarrhea rate of the two groups during the three months also showed statistically significant difference(P0.05). Conclusion The children rotavirus enteritis can be relieved and the diarrhea process can be shortened by adding oral Zinc Gluconate on the basis of the conventional treatment.This can also prevent diarrhea from recurring in the following 3 months,for which this method is worth of promoting.