The change of large arterial compliance in prehypertensive people

Objective: To investigate the changes of large arterial compliance in prehypertensive people. Methods: The 147 persons including appearance healthy and Ⅰ-Ⅱ hypertensives without any damaged target organ were divided into three groups: 54 nor-motensive persons, 57 prehypertensive persons and 36 hypertensive patients. Their pulse wave velocities (PWV) were measured by the Complior SP including carotid - radial ( C - RPWV) and carotid - femoral (C - FPWV). The other parameters involved in age, systolic blood pressure (SBP) , diastolic blood pressure (DBP) , pulse pressure (PP) , weight, height, body mass index (BMI) , waist a-round, buttocks around, ratio of waist around to buttocks around and heart rates (HR). Results: C - FPWV, C - RPWV of normoten-sive group, prehypertensive group, hypertensive group are (8. 82±1.60) m/s, (8.77± 1.07) m/s; (9.66±1.60) m/s, (9.78±1. 48) m/s; and (10.07±1.45) m/s ,(10.51±1.64) m/s. One - way ANOVA analysis showed that most of factors have statistical significances between the three groups instead of HR. S - N - K test between two groups showed that weight, height, BMI, their ratio of waist and buttocks around, C - RPWV and C - FPWV in prehypertensive group were higher than those of normotensive group, P 0. 05; and its C - RPWV was lower than those of hypertensive group, P 0.05. In normal people (normotensive and prehypertensive group) , C -FPWV and C - RPWV had correlations with age, SBP, C - RPWV and HR, and C - FPWV associated with PP, P 0.05. The multiple factors regressive analysis showed that C - FPWV had the intimacy with age, SBP, PP and weight; C - RPWV had the intimacy with DBP and HR. Conclusions: There is the change of large arterial compliance in prehypertensive patients. Arterial compliance decreases with the increase of age, blood pressure, and heart rate in nonhypertensive patients.