The impact of RouGanJianPi Decoction on the bone density of deovarium female rats with osteoporosis

Objective To evaluate the effect and security of RouGanJianPi prescription for osteoporosis which was made by authors.Method Multicentric randomized double-blind and double-simulation-compared clinical observation from July 2005 to July 2007.Also systemic clinical research on 242 primary osteoporosis patients was taken.Result In the treatment group(i.e RouGanJianPi Decoction group) there was obvious effect.There was great difference between the two groups and the treatment group was obviously superior to the control group in improving waist and knee ache and walk difficulty and in the change of lumbar bone density.In addition,there was no obvious untoward effect in treatment group during treatment and there was no change on all kinds of blood biochemical indicator and EKG.Conclusion RouGanJianPi prescription is a kind of safe and effective TCM-prescription on curing primary osteoporosis.