Ursodeoxycholic acid capsule for cholestatic hepatitis in 42 cases

Objective:To investigate the curative effect of ursodeoxycholic acid capsule for the treatment of cholestatic hepatitis.Methods:86 patients with cholestatic hepatitis were randomized into the treatment group and control group.The liver-protective complex treatment was used in both groups,besides this,the treatment group was added with ursodeoxycholic acid capsule 250 g three times daily.One course of treatment was 4 weeks,and three treatment courses were observed in two groups.Results:In the treatment group,26 cases were significantly effective,15 cases effective and one case ineffective,with a total effective rate of 97.6%;in the control group,18 cases were significantly effective,17 cases effective and 9 cases ineffective,with a total effective rate of 79.5%;the difference between two groups was significant(P0.05).The percentage of those patients whose TBil returned to normal in 4 weeks was 16.7% for the treatment and 6.9% for the control group,of those in 8 weeks 90.5% for the treatment group and 63.6% for the control group,of those not returning to normal in 12 weeks,9.3% for the treatment group and 36.4% for the control group.Conclusion:The curaitve effect of ursodeoxycholic acid capsule for cholestatic is good.