Effects of double devascularization procedure on hemodynamics and recent and long-term hepatic function of portal hypertensive patients

Objective: To investigate the effects of devascularization procedure on portal hemodynamics and recent and long-term hepatic function of portal hypertensive patients. Methods: A retrospective clinical analysis about portal hemodynamics and recent and long-term hepatic function was made in 367 cases of portal hypertensive patients, who admitted to our hospital and subjected to double devascularization from January 1989 to January 2008. Results: It was found that FPP was decreased from (36.2±4.2)cmH2O preoperatively to (31.4±3.3)cmH2O postoperatively (P0.05). The average velocity and blood flow quantity of portal vein were decreased postoperatively, which of hepatic artery contrarily were increased significantly (P0.05). Compared with the preoperative liver function, the postoperative liver function was no significant changes after 1 and 3 month (P0.05), but if was improved significantly after 6 and 12 month (P0.05). Conclusions: The double devascularization procedure can not only decrease portal vein pressure moderately but also strengthen the hepatic artery perfusion. It plays an important role on maintaining recent liver function and improving long-term liver function postoperatively.