2012Zhongguo xiandai yixue/Zhongguo xiandai yixue zazhiRequires access

Effects of modified surgical procedure on hepatic hemodynamics and hepatic function of portal hypertensive patients

Peng Xing-yu

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Abstract

【Objective】 To understand the effect and significance of modified surgical procedure on hepatic hemodynamic and hepatic function of portal hypertension.【Methods】 The liver reserve function and effective hepatic blood flow(EHBF) before and after surgery were measured by using retention rate of indocyanine green at fifteen minutes(ICG-R15),hepatic hemodynamic parameters was measured with hypersound measured after devascularization.【Results】 It was found that portal venous pressure was decrease obviously,the hepatic portal vein and hepatic effective blood flow conspicuous reduced after devascularization 1 month and 3 month(P 0.05);and hepatic reserve function no significant changes(P 0.05).【Conclusion】 ICG is a safe,simple and sensitive method on measure liver reserve function,and the liver reserve function no significant changes after devascularization;modified surgical procedure can maintain blood supply of liver and liver function and the operating method is safe,effective and reasonable.

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【Objective】 To understand the effect and significance of modified surgical procedure on hepatic hemodynamic and hepatic function of portal hypertension.【Methods】 The liver reserve function and effective hepatic blood flow(EHBF) before and after surgery were measured by using retention rate of indocyanine green at fifteen minutes(ICG-R15),hepatic hemodynamic parameters was measured with hypersound measured after devascularization.【Results】 It was found that portal venous pressure was decrease obviously,the hepatic portal vein and hepatic effective blood flow conspicuous reduced after devascularization 1 month and 3 month(P 0.05);and hepatic reserve function no significant changes(P 0.05).【Conclusion】 ICG is a safe,simple and sensitive method on measure liver reserve function,and the liver reserve function no significant changes after devascularization;modified surgical procedure can maintain blood supply of liver and liver function and the operating method is safe,effective and reasonable.

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Available abstract

【Objective】 To understand the effect and significance of modified surgical procedure on hepatic hemodynamic and hepatic function of portal hypertension.【Methods】 The liver reserve function and effective hepatic blood flow(EHBF) before and after surgery were measured by using retention rate of indocyanine green at fifteen minutes(ICG-R15),hepatic hemodynamic parameters was measured with hypersound measured after devascularization.【Results】 It was found that portal venous pressure was decrease obviously,the hepatic portal vein and hepatic effective blood flow conspicuous reduced after devascularization 1 month and 3 month(P 0.05);and hepatic reserve function no significant changes(P 0.05).【Conclusion】 ICG is a safe,simple and sensitive method on measure liver reserve function,and the liver reserve function no significant changes after devascularization;modified surgical procedure can maintain blood supply of liver and liver function and the operating method is safe,effective and reasonable.

Key concepts: Indocyanine green, Portal venous pressure, Hepatic function, Medicine, Liver function, Hemodynamics, Portal vein, Portal hypertension

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