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Determination of Ginsenoside Rg_1 and Notoginsenoside R_1 in Yirenchangtai Capsules by HPLC

Fang Wang

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Abstract

Objective:To determine Determination ginsenoside Rg1 and notoginsenoside R1in Yirenchangtai Capsules by HPLC.Method:The separation was performed on Agilent ZE-C18 column,using methyl cyanide-water(17∶83)as mobile phase.The detection wavelength was at 203 nm.The flow rate was 1.0 mL·min-1.Result:The linear range of ginsenoside Rg1 was 0.4-10.1 μg(r=0.999 6),The linear range of notoginsenoside R1 was 0.1-0.25 μg(r=0.999 6).The average recovery of ginsenoside Rg1 was 99.96%,RSD was 0.25%(n=6).The average recovery of notoginsenoside R1 was 100.03%,RSD was 0.23%(n=6).Conclusion: The method can determine the ginsenoside Rg1and notoginsenoside R1 The method was reliable and accura.

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Objective:To determine Determination ginsenoside Rg1 and notoginsenoside R1in Yirenchangtai Capsules by HPLC.Method:The separation was performed on Agilent ZE-C18 column,using methyl cyanide-water(17∶83)as mobile phase.The detection wavelength was at 203 nm.The flow rate was 1.0 mL·min-1.Result:The linear range of ginsenoside Rg1 was 0.4-10.1 μg(r=0.999 6),The linear range of notoginsenoside R1 was 0.1-0.25 μg(r=0.999 6).The average recovery of ginsenoside Rg1 was 99.96%,RSD was 0.25%(n=6).The average recovery of notoginsenoside R1 was 100.03%,RSD was 0.23%(n=6).Conclusion: The method can determine the ginsenoside Rg1and notoginsenoside R1 The method was reliable and accura.

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Available abstract

Objective:To determine Determination ginsenoside Rg1 and notoginsenoside R1in Yirenchangtai Capsules by HPLC.Method:The separation was performed on Agilent ZE-C18 column,using methyl cyanide-water(17∶83)as mobile phase.The detection wavelength was at 203 nm.The flow rate was 1.0 mL·min-1.Result:The linear range of ginsenoside Rg1 was 0.4-10.1 μg(r=0.999 6),The linear range of notoginsenoside R1 was 0.1-0.25 μg(r=0.999 6).The average recovery of ginsenoside Rg1 was 99.96%,RSD was 0.25%(n=6).The average recovery of notoginsenoside R1 was 100.03%,RSD was 0.23%(n=6).Conclusion: The method can determine the ginsenoside Rg1and notoginsenoside R1 The method was reliable and accura.

Key concepts: Ginsenoside Rg1, Ginsenoside, Chromatography, High-performance liquid chromatography, Chemistry, Linear range, Linear relationship, Detection limit

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Determination of Ginsenoside Rg_1 and Notoginsenoside R_1 in Yirenchangtai Capsules by HPLC — Research Paper | ScholarLens