Comparison study of Citalopram and Citalopram combined with Risperidone in treatment of somatoform disorders

Objective To study the efficacy and safety of citalopram combined with risperidone in the treatment of somatoform disorders.Methods 101 patients were assigned to citalopram(control group,n=51)and citalopram combined with risperidone(study group,n=50),and treated for 8 weeks.Before treatment and at the ends of the week2、4、6、8,the clinical effects and side effects were assessed with SCL-90,HAMD,TESS.Results The score of SCL-90 and HAMD after the treatment of the study group and control group were lower than before treatment, which had a significant difference(P0.01).At the end of 8th week,effective rates of the study group and control group were respectively 82%and 54%,which had a significant difference(P0.01).There was difference in the effective time of drugs of the two groups(P0.01).Side effects of both the two group were milder,most occurred in the initial stage of treatment and gradually remitted via expectant treatment.Conclusion citalopram combined with risperidone in treatment of somatoform disorders takes effects better and faster than single citalopram and doesn't increase side effects.