The clinical study of ulinastatin combined with somatostatin in the treatment of acute pancreatitis

Objective To investigate the clinical effects of the treatment of acute pancreatitis by using ulinastatin combined with somatostatin.Methods A total of 240 cases of patients with acute pancreatitis admitted to our hospital from June,2010 to July,2011 were included in this study,patients were randomized to the treatment group and the control group,the control group with 120 cases accepted conventional therapy and the treatment group with 120 cases accepted conventional therapy plus the use of ulinastatin,then the clinical efficacy of the two treatments were observed.Results The treatment group and the control group are Compared in the cure rate,the total efficiency,the time of clinical remission and days of hospitalization,the differences were statistically significant(P 0.05 or P 0.01),treatment effect of the treatment group was significantly better than that of the control group;after a week ’s treatment,the test results(WBC,AMS and CRP test values) of the treatment group were significantly lower than those of the control group,there was significantly statistical dif ference(P 0.05) between the two groups.Conclusion The effect of the treatment of acute pancreatitis by using ulinastatin combined with somatostatin was significantly obvious,the treatment method can relieve the clinical symptoms quickly and control the developing of the disease,and reduce the complications of multiple organ,improving the cure rate,shorten ing the length of hospitalization,and saving the cost of hospitalization.Therefore,the treatment of acute pancreatitis by us ing somatostatin united ulinastatin was worthy of wide application in clinic.