Treating 96 Cases of Ankylosing Spondylitis with Modified Bushen Zhuanggu Decoction

Objective:To observe the curative effect of modified Bushen Zhuanggu Decoction in the treatment of ankylosing spondylitis.Methods:192 cases of ankylosing spondylitis were randomly and equally divided into the traditional Chinese medicine(TCM) group and the Western medicine(WM) group.The TCM group according to the model were then divided into kidney deficiency and wet cold group(Group A),kidney deficiency and damp heat group(Group B).Group A 52 cases treated with Bushen Zhuanggu Quhan Decoction plus Western Placebo,group B 44 cases treated with Bushen Zhuanggu Qinghua Decoction plus Western Placebo.The WM group according to the model were then divided into kidney deficiency and wet cold group(Group C),kidney deficiency and damp heat group(Group D).Group C 49 cases treated with Sulfasalazine plus TCM Placebo,group D 47 cases treated with Sulfasalazine plus TCM Placebo.Each group were treated for 8 weeks,observing BAS-G,BASDAI,BASFI,night pain,spinal pain,and TCM syndrome score of the 4 groups before and after treatment.Efficacy evaluation was carried out by ASAS20 efficacy evaluation criteria.Results:The BAS-G,BASDAI,BASFI,night pain,spinal pain,and TCM syndrome score of all the groups improved after treatment(P 0.05 or P 0.01).The effective rate of the TCM group was higher than that of the WM group(P 0.05).Conclusion:The modified Bushen Zhuanggu Decoction had an obvious effect on the treatment of ankylosing spondylitis,reliable for clinical treatment.