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2007•Acta Academiae Medicinae XuzhouRequires access

The experience with 50 cases of orthotopic liver transplantation in rats

Lei Qin

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Abstract

Objective To establish a reliable model of orthotopic liver transplantation in rats.Methods After some rehearsal,50 procedures of rat orthotopic liver transplantation were performed by using modified Kamada′s two-cuffed technique.Results The 24-hour and 2-week survival rates of the model rats were 90% and 78% respectively.Conclusion Delicate and skillful surgical manipulation,smooth collaboration of the operating team,standardized protocol and some detailed modifications are the key to the success of rat liver transplantation.

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Objective To establish a reliable model of orthotopic liver transplantation in rats.Methods After some rehearsal,50 procedures of rat orthotopic liver transplantation were performed by using modified Kamada′s two-cuffed technique.Results The 24-hour and 2-week survival rates of the model rats were 90% and 78% respectively.Conclusion Delicate and skillful surgical manipulation,smooth collaboration of the operating team,standardized protocol and some detailed modifications are the key to the success of rat liver transplantation.

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Available abstract

Objective To establish a reliable model of orthotopic liver transplantation in rats.Methods After some rehearsal,50 procedures of rat orthotopic liver transplantation were performed by using modified Kamada′s two-cuffed technique.Results The 24-hour and 2-week survival rates of the model rats were 90% and 78% respectively.Conclusion Delicate and skillful surgical manipulation,smooth collaboration of the operating team,standardized protocol and some detailed modifications are the key to the success of rat liver transplantation.

Key concepts: Orthotopic liver transplantation, Liver transplantation, Medicine, Transplantation, Rat model, Surgery, Internal medicine

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