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Clinical and pathologic features study of 87 cases of gastrointestinal stromal tumor

Jianfang Liang

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Abstract

Objective To explore the clinical and pathological features of gastrointestinal stromal tumor(GIST).Methods All 87 cases of GIST were studied by HE and immunohistochemical staining methods.Clinicopathological findings were analysed in 62 cases of GIST combined with followe-up date.Results Among 87 cases of GIST,72 showed CD117 positive and 62 CD34 positive.According to Fletcher's scheme,the cases of GIST were divided into 4 subgroups:very low aggressive risk(n=17),low risk(n=23),intermediate risk(n=23) and high risk(n=24).Conclusions The GIST occurs predominantly in the middle and old age patients.CD117 positive immuno-staining only is a diagnositic marker of GIST,while the tumor size,mitotic count and coagulative necrosis can be seem as prognostic parameters.

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Objective To explore the clinical and pathological features of gastrointestinal stromal tumor(GIST).Methods All 87 cases of GIST were studied by HE and immunohistochemical staining methods.Clinicopathological findings were analysed in 62 cases of GIST combined with followe-up date.Results Among 87 cases of GIST,72 showed CD117 positive and 62 CD34 positive.According to Fletcher's scheme,the cases of GIST were divided into 4 subgroups:very low aggressive risk(n=17),low risk(n=23),intermediate risk(n=23) and high risk(n=24).Conclusions The GIST occurs predominantly in the middle and old age patients.CD117 positive immuno-staining only is a diagnositic marker of GIST,while the tumor size,mitotic count and coagulative necrosis can be seem as prognostic parameters.

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Available abstract

Objective To explore the clinical and pathological features of gastrointestinal stromal tumor(GIST).Methods All 87 cases of GIST were studied by HE and immunohistochemical staining methods.Clinicopathological findings were analysed in 62 cases of GIST combined with followe-up date.Results Among 87 cases of GIST,72 showed CD117 positive and 62 CD34 positive.According to Fletcher's scheme,the cases of GIST were divided into 4 subgroups:very low aggressive risk(n=17),low risk(n=23),intermediate risk(n=23) and high risk(n=24).Conclusions The GIST occurs predominantly in the middle and old age patients.CD117 positive immuno-staining only is a diagnositic marker of GIST,while the tumor size,mitotic count and coagulative necrosis can be seem as prognostic parameters.

Key concepts: GiST, CD117, CD34, Medicine, Pathological, Coagulative necrosis, Stromal tumor, Pathology

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