Clinical effects of freeze-dried rabies purified vaccine (Vero) in 120 outpatients

AIM: To observe the protective effect and the safety of freeze-dried rabies purified vaccine for human use (Vero) prepared from continuous cell line of African green monkey kidney (Vero cell). METHODS: 240 outpatients bitten by dog were randomly divided into two groups, the experiment group and the control group were vaccinated with the freeze-dried rabies purified vaccine for human u se (Vero cell) and the freeze-dried rabies purified vaccine for human use (PHK c ell) respectively according to the standard operation process of rabies vaccine. 15 d after vaccination, the neutralization antibody was tested and the adverse reactions were observed. RESULTS: The antibody level of experiment group (96.7 % ) was higher (P0.05) than the control group (90.0 %), whereas, the rate of the adverse reactions in experiment group (10.8 %) was lower (P0.05) than the compar e group (21.7%). CONCLUSION: The vaccination effect of rabies purified vaccine for human use (Vero) is better than rabies purified vaccine for human use (PHK c ell).