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2011•Unpublished venueRequires access

Bacteriostatic action of 11 fluoroquinolones to bacterium Aeromonas hydrophila

Yongli Zhang

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Abstract

In this experiment,agar diffusion method was used to study antibacterial effect of 11 fluoroqui-nolones(FQs)on Aeromonas hydrophila.The inhibition zone was measured,and the double tube dilution method was used to study minimum inhibitory concentration(MIC) and minimum bactericidal concentration(MBC).The results showed that Levofloxacin hydrochloride,Ofloxacin,and Sarafloxacin hydrochloride had better antibacterial effect on A.hydrophila,and the MIC of the three medicines were 0.012,0.024,0.024mg/L,respectively.The Enro-floxacin lactate,Enrofloxacin hydrochloride,and Ofloxacin had the same MBC value of 1.563 mg/L.

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What this paper is about

In this experiment,agar diffusion method was used to study antibacterial effect of 11 fluoroqui-nolones(FQs)on Aeromonas hydrophila.The inhibition zone was measured,and the double tube dilution method was used to study minimum inhibitory concentration(MIC) and minimum bactericidal concentration(MBC).The results showed that Levofloxacin hydrochloride,Ofloxacin,and Sarafloxacin hydrochloride had better antibacterial effect on A.hydrophila,and the MIC of the three medicines were 0.012,0.024,0.024mg/L,respectively.The Enro-floxacin lactate,Enrofloxacin hydrochloride,and Ofloxacin had the same MBC value of 1.563 mg/L.

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Available abstract

In this experiment,agar diffusion method was used to study antibacterial effect of 11 fluoroqui-nolones(FQs)on Aeromonas hydrophila.The inhibition zone was measured,and the double tube dilution method was used to study minimum inhibitory concentration(MIC) and minimum bactericidal concentration(MBC).The results showed that Levofloxacin hydrochloride,Ofloxacin,and Sarafloxacin hydrochloride had better antibacterial effect on A.hydrophila,and the MIC of the three medicines were 0.012,0.024,0.024mg/L,respectively.The Enro-floxacin lactate,Enrofloxacin hydrochloride,and Ofloxacin had the same MBC value of 1.563 mg/L.

Key concepts: Ofloxacin, Aeromonas hydrophila, Enrofloxacin, Levofloxacin, Minimum inhibitory concentration, Microbiology, Minimum bactericidal concentration, Chemistry

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