2012•Chinese Journal of General PracticeRequires access

Clinical Observation of Meng Lu Montelukast Sodium in the Treatment of Bronchiolitis

Xi Zhang

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Abstract

Objective To explore the clinical efficacy and safety of Meng Lu montelukast sodium in the treatment of bronchiolitis.Methods To my department of pediatrics,90 cases of infants with bronchiolitis were randomly divided into treatment group and control group,two groups were given conventional treatment.The treatment group was given Meng Lu montelukast sodium oral,6 months following 2.5 mg/d,4 mg/d more than 6 months,every night 1,children with cough,wheezing,shortness of breath,pulmonary symptoms improved time and length of hospital stay were observed and recorded.Results 31 cases in treatment group were cured(68.9%),improved in 11 cases(24.4%),invalid in 3 cases(6.7%),the total efficiency of 93.3%;23 cases in control group of were cured(51.1%),improved in 13 cases(28.9%),invalid in 9 cases(20%),with the total efficiency of 80%.The effective rate of treatment group(93.3%) was significantly higher than that in control group(80%),which had a significant difference(χ2=3.462,P0.05).Cough,wheezing,shortness of breath,group of pulmonary symptoms improved time and length of hospital stay in treatment group were significantly shorter than those of control group,the difference was statistically significant(P0.05).Conclusion Meng Lu montelukast sodium had curative effect,safety and reliability in treatment of capillary bronchitis,it was worthy of clinical use.

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Objective To explore the clinical efficacy and safety of Meng Lu montelukast sodium in the treatment of bronchiolitis.Methods To my department of pediatrics,90 cases of infants with bronchiolitis were randomly divided into treatment group and control group,two groups were given conventional treatment.The treatment group was given Meng Lu montelukast sodium oral,6 months following 2.5 mg/d,4 mg/d more than 6 months,every night 1,children with cough,wheezing,shortness of breath,pulmonary symptoms improved time and length of hospital stay were observed and recorded.Results 31 cases in treatment group were cured(68.9%),improved in 11 cases(24.4%),invalid in 3 cases(6.7%),the total efficiency of 93.3%;23 cases in control group of were cured(51.1%),improved in 13 cases(28.9%),invalid in 9 cases(20%),with the total efficiency of 80%.The effective rate of treatment group(93.3%) was significantly higher than that in control group(80%),which had a significant difference(χ2=3.462,P0.05).Cough,wheezing,shortness of breath,group of pulmonary symptoms improved time and length of hospital stay in treatment group were significantly shorter than those of control group,the difference was statistically significant(P0.05).Conclusion Meng Lu montelukast sodium had curative effect,safety and reliability in treatment of capillary bronchitis,it was worthy of clinical use.

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Available abstract

Objective To explore the clinical efficacy and safety of Meng Lu montelukast sodium in the treatment of bronchiolitis.Methods To my department of pediatrics,90 cases of infants with bronchiolitis were randomly divided into treatment group and control group,two groups were given conventional treatment.The treatment group was given Meng Lu montelukast sodium oral,6 months following 2.5 mg/d,4 mg/d more than 6 months,every night 1,children with cough,wheezing,shortness of breath,pulmonary symptoms improved time and length of hospital stay were observed and recorded.Results 31 cases in treatment group were cured(68.9%),improved in 11 cases(24.4%),invalid in 3 cases(6.7%),the total efficiency of 93.3%;23 cases in control group of were cured(51.1%),improved in 13 cases(28.9%),invalid in 9 cases(20%),with the total efficiency of 80%.The effective rate of treatment group(93.3%) was significantly higher than that in control group(80%),which had a significant difference(χ2=3.462,P0.05).Cough,wheezing,shortness of breath,group of pulmonary symptoms improved time and length of hospital stay in treatment group were significantly shorter than those of control group,the difference was statistically significant(P0.05).Conclusion Meng Lu montelukast sodium had curative effect,safety and reliability in treatment of capillary bronchitis,it was worthy of clinical use.

Key concepts: Medicine, Bronchiolitis, Montelukast, Clinical efficacy, Bronchitis, Anesthesia, Significant difference, Treatment and control groups

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