2013•Chinese Journal of Thrombosis and HemostasisRequires access
Curative Effects of Simvastatin in the Treatment of Acute Myocardial Infarction and its Influence on Hemorheology
Xinjie Wang
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Abstract
Objective To explore curative effects of simvastatin in the treatment of acute myocardial infarction and its influence on hemorheology.Methods 95 patients with acute myocardial infarction from June 2010 to June 2012 were divided randomly into control group and observe group.Patients in the control group were treated with routine therapy.Patients in the observe group were treated with simvastatin on the basis of routine therapy.The total effective rate and hemorheology index in the control group and observe group were analyzed.Results The total effective rate in the observe group were significantly higher than that in the control group(P 0.05).Compared with before treatment,the hemorheology index(fibrinogen,plasma viscosity,blood viscosity,platelet agglutination) had no significantly difference in the control group after treatment(P 0.05).The hemorheology index in the observe group after treatment significantly decreased than that before treatment and control group after treatment(P 0.05).Conclusion There is close relationship abnormal hemorheology and acute myocardial infarction.Simvastatin can significantly improve hemorheology index.