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2010•Zhongguo yiyuan ganranxue zazhiRequires access

Drug sensitivity and antibiotics resistance of Acinetobacter baumannii.

XU Jian-min, Xiong WenQi, Jianfeng Zheng, Ming Wei, Wen Gan

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Abstract

OBJECTIVE To investigate the pathogens distribution and drug resistance of 53 patients with Acinetobacter baumannii isolated from 2006 to 2009,and to provide basis for clinicians to select antibiotics correctly.METHODS Antimicrobial susceptibility tests on 53 strains of A.baumannii were proceeded by K-B disk diffusion test with 8 kinds of antibiotics.RESULTS In all of antibiotics,the highest of antimicrobial activity rate was imipenem,with the resistant rate 30.2%,sensitivity rate 81.1%.The second were cefoperazone/sulbactam and ceftazidime,and the resistant rates were 30.2% and 44.7% respectively.The resistant rates of the others were 70-80%.CONCLUSION Imipenem,cefoperazone/sulbactam and ceftazidime can be chosen to cure A.baumannii infections.As for resistant to carbopenems cases,cefoperazone/sulbactam and ampicillin/sulbactam may be used for therapy infection caused by A.baumannii.

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OBJECTIVE To investigate the pathogens distribution and drug resistance of 53 patients with Acinetobacter baumannii isolated from 2006 to 2009,and to provide basis for clinicians to select antibiotics correctly.METHODS Antimicrobial susceptibility tests on 53 strains of A.baumannii were proceeded by K-B disk diffusion test with 8 kinds of antibiotics.RESULTS In all of antibiotics,the highest of antimicrobial activity rate was imipenem,with the resistant rate 30.2%,sensitivity rate 81.1%.The second were cefoperazone/sulbactam and ceftazidime,and the resistant rates were 30.2% and 44.7% respectively.The resistant rates of the others were 70-80%.CONCLUSION Imipenem,cefoperazone/sulbactam and ceftazidime can be chosen to cure A.baumannii infections.As for resistant to carbopenems cases,cefoperazone/sulbactam and ampicillin/sulbactam may be used for therapy infection caused by A.baumannii.

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Available abstract

OBJECTIVE To investigate the pathogens distribution and drug resistance of 53 patients with Acinetobacter baumannii isolated from 2006 to 2009,and to provide basis for clinicians to select antibiotics correctly.METHODS Antimicrobial susceptibility tests on 53 strains of A.baumannii were proceeded by K-B disk diffusion test with 8 kinds of antibiotics.RESULTS In all of antibiotics,the highest of antimicrobial activity rate was imipenem,with the resistant rate 30.2%,sensitivity rate 81.1%.The second were cefoperazone/sulbactam and ceftazidime,and the resistant rates were 30.2% and 44.7% respectively.The resistant rates of the others were 70-80%.CONCLUSION Imipenem,cefoperazone/sulbactam and ceftazidime can be chosen to cure A.baumannii infections.As for resistant to carbopenems cases,cefoperazone/sulbactam and ampicillin/sulbactam may be used for therapy infection caused by A.baumannii.

Key concepts: Cefoperazone, Sulbactam, Acinetobacter baumannii, Imipenem, Antibiotics, Microbiology, Ceftazidime, Ampicillin

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