Analysis of drug resistance of imipenem-resistant acinetobacter baumannii

Objective To investigate the resistance of imipenem-resistant acinetobacter baumannii to18 commonly used antimicrobial agents.Methods MicroScan WalkAway-40 automatic microbial analysis system was applied to species identification and drug susceptibility test.The sensitivity detection of cefoperazone/sulbactam and minocycline was performed by K-B disk diffusion method.Results The lowest resistance rate of imipenem-resistant acinetobacter baumannii to cefoperazone/sulbactam was 37.5%,followed was minocycline(54.7%).All isolates showed 100.0% resistance to cefotaxime,cefatriaxone,piperacillin,piperacillin/tazobactam and ticarcillin/clavulanic acid.The resistance to other antimicrobial agents was more than 81.1%.Conclusion All imipenem-resistant acinetobacter baumannii isolates are highly resistant to multiple antibiotics,part of them are pan-resistant isolates.The resistance to cefoperazone/sulbactam is lower than other antimicrobial agents.