Establishment and evaluation of the clinical reportable range of BUN detected by Olympus AU5400 automatic analyzer

Objective To establish and evaluate the clinical reportable range of BUN detected by Olympus AU5400 automatic analyzer.Methods Referring to CLSI EP6-A guideline and pertinent literature,we performed the validate experiments of analytical measurement range and max dilution limit by Olympus AU5400 automatic analyzer.The clinical reportable range was established with above results combining functional sensitivity.Results The analytical measurement range of BUN was 0.60-47.01mmol/L.The max dilution limit was 1:50 and the clinical reportable range was 0.66-2350.5mmol/L.Conclusions Olympus AU5400 automatic analyzer has broad linearity range,and its results show better sensitive and accurate,which is suited for detecting BUN in routine.