Drug Resistance Analysis of Klebsiella pheumoniae Infection in Our Hospital from 2009-2011

Objective To explore the resistance of Klebsiella pneumoniae isolated from 2009 to 2011 in our hospital and provide the guidance for the clinical treatment.Methods A total of 1069 Klebsiella pneumoniae isolated in clinic were collected during 2009-2011,the results of susceptibility test of Klebsiella pneumoniae were analyzed statistically.Results The different drug resistance to commonly used antibiotics occurred in 1069 strains of Klebsiella pneumoniae.Drugs which the average resistance rate was above 50% were ampicillin(96.33%),cefazolin(85.97%),cefuroxime(74.60%),cotrimoxazole(73.63%),and gentamicin(52.80%).Drugs which the resistance rate was much lower were imipenem(0.53%),meropenem(1.07%),ciprofloxacin(2.97%),tazobactam sodium/piperacillin sodium(5.20%) and amikacin(5.47%).Conclusion The antimicrobial resistance of Klebsiella pneumoniae has increased.The management of antibiotics should be strengthened and the occurrence and prevalence of the drug resistant strains should be strictly controlled.