Pharmacoeconomic analysis of moxifloxacin vs Sparfloxacin in treatment of urinary tract infection

OBJECTIVE To discuss the economic efficiency of moxifioxacin vs sparfloxacin in the treatment of urinary tract infection.METHODS The trial design was random,open,and parallel control.195 patients with urinary tract infection were involved.176 cases evaluated were randomly divided into the treatment group or the control.90 patients in treatment group were given 400mg moxifloxacin capsule for 14d,while 86 patients in control group were given 200mg sparfloxacin capsule for 14d.RESULTS The total clinical effective rate of treatment group and control group were 97.8% and 91.9%,the bacterial eliminating rate were 96.7% and 94.2%,and the rate of adverse reaction were 7.78% and 9.30%,respectively.There was no significant difference between two groups(P0.05).The cost-effectiveness ratio of moxifloxacin was 4.16 and l.72 for sparfloxacin(P0.01).CONCLUSIONS The therapeutic scheme of sparfloxacin seems to be the better one for treating urinary tract infection.