Cost-effectiveness analysis of moxifloxacin and levofloxacin for treatment of urinary tract infection

Objective To estimate the curative effect,adverse reaction and cost-effectiveness of moxifloxacin and levofloxacin for treatment of urinary tract infection.Methods The trial design was random,open,and parallel control.195 patients with urinary tract infection were involved.176 cases evaluated were randomly divided into the treatment group and the control group.90 patients in treatment group were given 400 mg moxifloxacin capsule for 10 d,while 86 patients in control group were given 200 mg levofloxacin capsule twice a day for 7-14 d.Results The total clinical effective rate of case and control group were 97.8% and 91.9% respectively,and the bacterial eliminating rate were 96.7% and 94.2% respectively,and the rate of adverse reaction were 7.78% and 9.30% respectively.There was no significant difference between two groups(P0.05).The cost-effectiveness ratio of moxifloxacin was 2.67 and 0.51 for levofloxacin(P0.01).Conclusion The therapeutic scheme of levofloxacin seems to be the best one for treating urinary tract infection.