Observation on the Effect of Triple Therapy in the Treatment of 80 Elderly Patients with Peptic Ulcer

Objective To explore the clinical analysis of omeprazole, clarithromycin and amoxicillin(triple therapy) in the treatment of peptic ulcer in the elderly. Methods 80 cases with peptic ulcer admitted in our hospital from June 2009 to August 2013 were selected as the subjects of this study and they were divided into the observation group and the control group with 40 cases in each according to the random double-blind method. The control group was treated by metronidazole combined with amoxicillin, and the observation group was treated by omeprazole, clarithromycin and amoxicillin. The course of treatment of both groups was 4 weeks.All the patients underwent gastroscopy for reviewing. The ulcer healing and the detected result of clearing Helicobacter pylori(HP)were compared between the groups. Results After treatment, the ulcer healing and clearance of Helicobacter pylori were significantly better than those of the control group(P0.05), and abdominal distention, acid regurgitation and other performance were less than those of the control group(P0.05). Conclusion Omeprazole, clarithromycin combined with amoxicillin has better treatment effect on peptic ulcer in the elderly, which can improve the clearance rate of Helicobacter pylori, so it is worthy of clinical appli-cation and promotion.