2008•The Journal of Clinical PsychiatryRequires access

A comparison study of ziprasidone and risperidone in treatment of schizophrenia

Xie Pei-lian

Abstract

Objective:To evaluate the efficacy and side effects of ziprasidone in treatment of schizophrenia.Method:According to hospitalization sequence,80 patients with schizophrenia were randomly divided into two groups,ziprasidone group(n=40)and resperidone group(n=40)were treated for 6 weeks.The efficacy and side effects were evaluated by positive and negative symptoms scale(PANSS)and treatment emergent symptoms scale(TESS)and rating scale for extrapyramidel side effects(RSESE)respectively.Results:The efficacy was similar for ziprasidone and risperidone.Extrapramidal side effects in patients of ziprasidone group were significantly fewer.Conclusion:Ziprasidone was a antipsychotic with better efficacy and tolerance and less side effects.

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Key concepts: Ziprasidone, Risperidone, Schizophrenia (object-oriented programming), Negative symptom, Side effect (computer science), Antipsychotic, Psychology, Internal medicine