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The clinical significance of coagulation index and D-D detection in patients with cirrhosis

Wang Hou-zha

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Abstract

Objective To explore the clinical significance of detecting prohtrombin time(PT),actived partial thromboplatin time(APTT),fibrinogen(FIB),thrombin time(TT)and D-dimer(D-D)in the patients with cirrhosis.Methods PT,APTT,FIB,TT and D-D were detected in 85 patients with cirrhosis and 60 healthy people by IL ACL-TOP Auto Blood Coagulation Analyzer.Results The PT,APTT,TT prolonged,FIB decreased and D-D increased in the patients compared with the control,and showed significant difference(P0.01).Conclusion The coagulation index and D-D detection has a reference value in estimating the coagulation function,the hemorrhagic tendency,the treatment and prognosis in the patients with cirrhosis.

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What this paper is about

Objective To explore the clinical significance of detecting prohtrombin time(PT),actived partial thromboplatin time(APTT),fibrinogen(FIB),thrombin time(TT)and D-dimer(D-D)in the patients with cirrhosis.Methods PT,APTT,FIB,TT and D-D were detected in 85 patients with cirrhosis and 60 healthy people by IL ACL-TOP Auto Blood Coagulation Analyzer.Results The PT,APTT,TT prolonged,FIB decreased and D-D increased in the patients compared with the control,and showed significant difference(P0.01).Conclusion The coagulation index and D-D detection has a reference value in estimating the coagulation function,the hemorrhagic tendency,the treatment and prognosis in the patients with cirrhosis.

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Available abstract

Objective To explore the clinical significance of detecting prohtrombin time(PT),actived partial thromboplatin time(APTT),fibrinogen(FIB),thrombin time(TT)and D-dimer(D-D)in the patients with cirrhosis.Methods PT,APTT,FIB,TT and D-D were detected in 85 patients with cirrhosis and 60 healthy people by IL ACL-TOP Auto Blood Coagulation Analyzer.Results The PT,APTT,TT prolonged,FIB decreased and D-D increased in the patients compared with the control,and showed significant difference(P0.01).Conclusion The coagulation index and D-D detection has a reference value in estimating the coagulation function,the hemorrhagic tendency,the treatment and prognosis in the patients with cirrhosis.

Key concepts: Fibrinogen, Cirrhosis, Medicine, Thrombin time, Internal medicine, Coagulation, Gastroenterology, Prothrombin time

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