Evaluation of Cefoperazone/Sulbactam in the Treatment of Chest Postoperative Infection

OBJECTIVE To evaluate cefoperazone/sulbactam′s therapeutic value in the treatment of chest postoperative infection. METHODS From 49 patients with lower respiratory tract or thoracic cavity infection after chest operation andyzeal retrospectively, 32 patients were treated with cefoperazone/sulbactam. RESULTS Most lower respiratory tract and thoracic cavity infection after chest operation were caused by Gram negative conditioned pathogen, the sensitive rate of these pathogenic bacilli to cefoperazone/sulbactam was 81.58%, and the resistance rate was 7.89%, there was no evident difference with imipenem (P0.05), but had significantly difference with other antibiotics in drug sensitivity experiment (P0.05). The overall effective rate of cefoperazone/sulbactam was 93.75% in clinics. CONCLUSIONS Cefoperazone/sulbactam was worth recommending to use in patients with lower respiratory tract or thoracic cavity infection after chest operation.