2006Zhongguo yiyuan ganranxue zazhiRequires access

Efficacy and Safety of Cefoperazone/sulbactam in Treatment of Lower Respiratory Tract Infections of Elderly: A Clinical Study Compared with Cefoperazone

Wang Xiao-ge

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Abstract

OBJECTIVE To evaluate the efficacy and safety of cefoperazone/sulbactam in comparison with cefoperazone in(treatment) of lower respiratory tract infections of elderly.METHODS Eighty six patients((seventy) years old) with lung infections were equally divided into two groups:cefoperazone/sulbactam group and cefoperazone group in a regimen of 1.0-2.0 g,twice daily for 5-14 days.RESULTS The effective rate of both agents were 100% and 80%,and their ADRs incidence rate of elderly was 4.98% and 25.00%, respectively.There were statistically significant difference(P(0.05)).CONCLUSIONS From results of this study it can be(concluded) that cefoperazone/sulbactam is an effective and safe drug for treatment of lung infection of elderly.

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OBJECTIVE To evaluate the efficacy and safety of cefoperazone/sulbactam in comparison with cefoperazone in(treatment) of lower respiratory tract infections of elderly.METHODS Eighty six patients((seventy) years old) with lung infections were equally divided into two groups:cefoperazone/sulbactam group and cefoperazone group in a regimen of 1.0-2.0 g,twice daily for 5-14 days.RESULTS The effective rate of both agents were 100% and 80%,and their ADRs incidence rate of elderly was 4.98% and 25.00%, respectively.There were statistically significant difference(P(0.05)).CONCLUSIONS From results of this study it can be(concluded) that cefoperazone/sulbactam is an effective and safe drug for treatment of lung infection of elderly.

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Available abstract

OBJECTIVE To evaluate the efficacy and safety of cefoperazone/sulbactam in comparison with cefoperazone in(treatment) of lower respiratory tract infections of elderly.METHODS Eighty six patients((seventy) years old) with lung infections were equally divided into two groups:cefoperazone/sulbactam group and cefoperazone group in a regimen of 1.0-2.0 g,twice daily for 5-14 days.RESULTS The effective rate of both agents were 100% and 80%,and their ADRs incidence rate of elderly was 4.98% and 25.00%, respectively.There were statistically significant difference(P(0.05)).CONCLUSIONS From results of this study it can be(concluded) that cefoperazone/sulbactam is an effective and safe drug for treatment of lung infection of elderly.

Key concepts: Cefoperazone, Medicine, Sulbactam, Internal medicine, Regimen, Incidence (geometry), Respiratory tract infections, Respiratory tract

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