2012•Unpublished venueRequires access

Efficacy of moxifloxacin injection in treatment of acute bacterial infection of urinary tracts

Sun Yun-fen

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Abstract

Objective To evaluate the efficacy and safety of moxifloxacin injection in the treatment of urinary tract bacterial acute infection.Methods A single blind randomized controlled trial was conducted 62 patients with urinary tract infections.The treatment group(n=31) were treated with moxifloxacin and the control group(n=31) were given levofloxacinfor 7~10d.Clinical,bacteriological efficacy and adverse reaction rates were compared.Results The recovery rate and effective rate were 90.3% and 96.8%in treatment group,and 87.1% and 93.5% in control group respectively(P0.05).The bacterial eradication rate in treatment group and in control group were 93.1% and 89.3%,and the adverse drug reaction rate in treatment group and in control group were 9.6% and 12.9% respectively(P0.05).Conclusion Moxifloxacin injection is effective and safe in treatment of acute bacterial infection of urinary tract.

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Objective To evaluate the efficacy and safety of moxifloxacin injection in the treatment of urinary tract bacterial acute infection.Methods A single blind randomized controlled trial was conducted 62 patients with urinary tract infections.The treatment group(n=31) were treated with moxifloxacin and the control group(n=31) were given levofloxacinfor 7~10d.Clinical,bacteriological efficacy and adverse reaction rates were compared.Results The recovery rate and effective rate were 90.3% and 96.8%in treatment group,and 87.1% and 93.5% in control group respectively(P0.05).The bacterial eradication rate in treatment group and in control group were 93.1% and 89.3%,and the adverse drug reaction rate in treatment group and in control group were 9.6% and 12.9% respectively(P0.05).Conclusion Moxifloxacin injection is effective and safe in treatment of acute bacterial infection of urinary tract.

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Available abstract

Objective To evaluate the efficacy and safety of moxifloxacin injection in the treatment of urinary tract bacterial acute infection.Methods A single blind randomized controlled trial was conducted 62 patients with urinary tract infections.The treatment group(n=31) were treated with moxifloxacin and the control group(n=31) were given levofloxacinfor 7~10d.Clinical,bacteriological efficacy and adverse reaction rates were compared.Results The recovery rate and effective rate were 90.3% and 96.8%in treatment group,and 87.1% and 93.5% in control group respectively(P0.05).The bacterial eradication rate in treatment group and in control group were 93.1% and 89.3%,and the adverse drug reaction rate in treatment group and in control group were 9.6% and 12.9% respectively(P0.05).Conclusion Moxifloxacin injection is effective and safe in treatment of acute bacterial infection of urinary tract.

Key concepts: Medicine, Moxifloxacin, Urinary system, Adverse effect, Internal medicine, Antibiotics, Gastroenterology, Surgery

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