2007Linchan huaxue yu gongyeRequires access

Study on Chemical Constituents of Semen Pharbitidis(II)

Ping Li

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Abstract

The active constituents in semen pharbitidis were studied.Seperation and purification were performed on columns of silica gel and Sephadex LH-20,and the chemical structures were elucidated by various spectroscopic data.Eight compounds were isolated from ethyl acetate fraction of 70 %(volume fraction) ethanol extract,and identified as cinnamic acid(Ⅰ),ferulic acid(Ⅱ),chlorogenic acid(Ⅲ),methyl chloroformate(Ⅳ),propyl chloroformate(Ⅴ),rhein(Ⅵ),12-hydroxy-methyl abieformate(Ⅶ) and 12-hydroxy-hydromethylabieformate(Ⅷ).These compounds were isolated from the genus Pharbitis for the first time by search.

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The active constituents in semen pharbitidis were studied.Seperation and purification were performed on columns of silica gel and Sephadex LH-20,and the chemical structures were elucidated by various spectroscopic data.Eight compounds were isolated from ethyl acetate fraction of 70 %(volume fraction) ethanol extract,and identified as cinnamic acid(Ⅰ),ferulic acid(Ⅱ),chlorogenic acid(Ⅲ),methyl chloroformate(Ⅳ),propyl chloroformate(Ⅴ),rhein(Ⅵ),12-hydroxy-methyl abieformate(Ⅶ) and 12-hydroxy-hydromethylabieformate(Ⅷ).These compounds were isolated from the genus Pharbitis for the first time by search.

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Available abstract

The active constituents in semen pharbitidis were studied.Seperation and purification were performed on columns of silica gel and Sephadex LH-20,and the chemical structures were elucidated by various spectroscopic data.Eight compounds were isolated from ethyl acetate fraction of 70 %(volume fraction) ethanol extract,and identified as cinnamic acid(Ⅰ),ferulic acid(Ⅱ),chlorogenic acid(Ⅲ),methyl chloroformate(Ⅳ),propyl chloroformate(Ⅴ),rhein(Ⅵ),12-hydroxy-methyl abieformate(Ⅶ) and 12-hydroxy-hydromethylabieformate(Ⅷ).These compounds were isolated from the genus Pharbitis for the first time by search.

Key concepts: Chemistry, Sephadex, Ethyl chloroformate, Ethyl acetate, Chromatography, Ferulic acid, Silica gel, Ethanol

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