Limbal epithelial autograft transplantation combined mitomycin C application for the treatment of pterygium

Objective To investigate the effects of limbal epithelial autograft transplantation combined mitomycin C application in preventing the recurrence of pterygium. Methods After cut of pterygium,the sclera was covered by a tampon with 0.4 mg/mL mitomycin C for 3 minutes and washed by physical solution,then limbal epithelial autograft was transplanted to the area.The follow-up time was 6-22 months. Results For all of the 42 eyes,pterygium recurred in 2 eyes(4.8%).The complications included foreign body sensation,tearing,delayed conjunctival healing,punctate keratitis,and dry eye syndrome.Conclusion Limbal epithelial autograft transplantation combined mitomycin C application can effectively prevent the recurrence of pterygium.It is simple,safe and has lower complications.