Clinical Distribution and Resistance Analysis of 176 Strains Staphylococcus Aureus Infection

Objective:To explore the infectious distribution and resistance profile of staphylococcus aureus infection occurred in our hospital in the recent three years.Method:Investigations of the distribution situation of specimen and department were made to the 176 strains bacteria isolated from our hospital,whose drug-susceptibilities were performed by Kirby-Bauer method and performed analysis of results.Result:Of 176 strains of isolated staphylococcus aureus,125 strains were MRSA,accouinting for 71.0%.100% of MRSA were resistant to penicillin G but susceptible to vancomycin,vancomycin and linezolid.Resistance of MRSA to chloramphenicol,trimethoprim were 18.4%,12.8%,respectively.The resistance rate to macrolides,aminoglycoside,clindamycin was even higher(77.6%-94.4%) and there was a multiple resistance.The resistance rate of MRSA was significantly higher than that of MSSA.Conclusion:Staphylococcus aureus,especially MRSA,are multidrug-resistant to commonly used antimicrobial agents.Their drug resistance shoud be monitored and controlled closely.The therapy towards infection of staphylococcus aureus should be applied reasonably according to the drug sensitive test so as to slow down the emergence of VISA and VRSA.