2015Zhōnghuá yàoxué zázhìRequires access

Chemical Constituents from Lythrum salicaria L.

Bei Jiang

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Abstract

OBJECTIVE To investigate the chemical constituents from the stems of Lythrum salicaria L.. METHODS The constituents were isolated and purified by silica gel,Sephadex LH- 20 column chromatography,and TLC. The structures were identified on the basis of spectral data and physiochemical characteristics. RESULTS Twenty compounds were isolated from 70% ethanol extracts and identified as betulinic acid( 1),2α,3α,24-trihydroxy-12( 13)-en-urs-28-oic acid( 2),6-O-( E)- sinapoylpoligalitol( 3),feruloyl-6'-O-α-D-glucopyranoside( 4),7-oxo-β-sitosterol( 5),en-tisolariciresinol( 6),muramine( 7),aesculetin( 8),apigenin( 9),( 2E,6S)-2,6-dimethyl-6-O-β-D-xylpyranosyloxy-2,7-menthiafolic acid( 10), quercetin3-O-( 6″-caffeoyl)-β-D-galactopyranoside( 11),cycloart-23-ene-3β,25-diol( 12),( 1'S,6'R)-8'-hydroxyabscisic acid-β-D-glucoside( 13),3',5-dihydroxy-3,6,4'-trimethoxyl-7-O-β-D-glucopyranoside flavonoid( 14),aurantiamide acetate( 15),5,6,3',4'-tetrahydroxy-3,7-dimethoxy-flavone( 16),ursolic acid( 17),oleanolic acid( 18),4-O-11-methyl-oleoside-p-hydroxyphenyl-( 6'-11-methyloleoside)-β-D-glucopyranoside( 19),and 6-O-galloylarbutin( 20). CONCLUSION Except for compounds 8 and 9,all the compounds were isolated from this plant material for the first time.

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What this paper is about

OBJECTIVE To investigate the chemical constituents from the stems of Lythrum salicaria L.. METHODS The constituents were isolated and purified by silica gel,Sephadex LH- 20 column chromatography,and TLC. The structures were identified on the basis of spectral data and physiochemical characteristics. RESULTS Twenty compounds were isolated from 70% ethanol extracts and identified as betulinic acid( 1),2α,3α,24-trihydroxy-12( 13)-en-urs-28-oic acid( 2),6-O-( E)- sinapoylpoligalitol( 3),feruloyl-6'-O-α-D-glucopyranoside( 4),7-oxo-β-sitosterol( 5),en-tisolariciresinol( 6),muramine( 7),aesculetin( 8),apigenin( 9),( 2E,6S)-2,6-dimethyl-6-O-β-D-xylpyranosyloxy-2,7-menthiafolic acid( 10), quercetin3-O-( 6″-caffeoyl)-β-D-galactopyranoside( 11),cycloart-23-ene-3β,25-diol( 12),( 1'S,6'R)-8'-hydroxyabscisic acid-β-D-glucoside( 13),3',5-dihydroxy-3,6,4'-trimethoxyl-7-O-β-D-glucopyranoside flavonoid( 14),aurantiamide acetate( 15),5,6,3',4'-tetrahydroxy-3,7-dimethoxy-flavone( 16),ursolic acid( 17),oleanolic acid( 18),4-O-11-methyl-oleoside-p-hydroxyphenyl-( 6'-11-methyloleoside)-β-D-glucopyranoside( 19),and 6-O-galloylarbutin( 20). CONCLUSION Except for compounds 8 and 9,all the compounds were isolated from this plant material for the first time.

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Available abstract

OBJECTIVE To investigate the chemical constituents from the stems of Lythrum salicaria L.. METHODS The constituents were isolated and purified by silica gel,Sephadex LH- 20 column chromatography,and TLC. The structures were identified on the basis of spectral data and physiochemical characteristics. RESULTS Twenty compounds were isolated from 70% ethanol extracts and identified as betulinic acid( 1),2α,3α,24-trihydroxy-12( 13)-en-urs-28-oic acid( 2),6-O-( E)- sinapoylpoligalitol( 3),feruloyl-6'-O-α-D-glucopyranoside( 4),7-oxo-β-sitosterol( 5),en-tisolariciresinol( 6),muramine( 7),aesculetin( 8),apigenin( 9),( 2E,6S)-2,6-dimethyl-6-O-β-D-xylpyranosyloxy-2,7-menthiafolic acid( 10), quercetin3-O-( 6″-caffeoyl)-β-D-galactopyranoside( 11),cycloart-23-ene-3β,25-diol( 12),( 1'S,6'R)-8'-hydroxyabscisic acid-β-D-glucoside( 13),3',5-dihydroxy-3,6,4'-trimethoxyl-7-O-β-D-glucopyranoside flavonoid( 14),aurantiamide acetate( 15),5,6,3',4'-tetrahydroxy-3,7-dimethoxy-flavone( 16),ursolic acid( 17),oleanolic acid( 18),4-O-11-methyl-oleoside-p-hydroxyphenyl-( 6'-11-methyloleoside)-β-D-glucopyranoside( 19),and 6-O-galloylarbutin( 20). CONCLUSION Except for compounds 8 and 9,all the compounds were isolated from this plant material for the first time.

Key concepts: Betulinic acid, Oleanolic acid, Sephadex, Chemistry, Ursolic acid, Apigenin, Column chromatography, Flavonoid

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