Chemical constituents from leaves of Lonicera macckii

Objective To study the chemical constituents from the leaves of Lonicera macckii. Methods The compounds were isolated and purified gel column chromatography, Sephadex LH-2 column chromatography and recrystallization, and their structures were identified by spectral analyses and physiochemical properties. Results Twelve compounds were isolated and identified as kaempferol (1), apigenin (2), hyperoside (3), apigenin-7-O-β-D-glucopyranoside (4), chrysoeri-ol-4′-O-β-D-glucopyranoside (5), luteolin-7-O-β-D-glucopyranoside (6), secologanin acid (7), sweroside (8), methyl 3,5-O-dicaffeoylquinate (9), oleanolic acid (10), β-sitosterol (11), and daucosterol (12), respectively. Conclusion Compounds 1—6 and 8—12 are isolated from this plant for the first time, and compound 5 is isolated from this genus for the first time.