2016Zhōnghuá yàoxué zázhìRequires access

Chemical constituents from the aerial parts of ribes diacanthum pall

Baoping Zhou, Chunlei Zhang, Xiao-Han Zou, Jian Xu, Yan Li, Xichun Li, Chengzhi Chai, Zhengyu Cao

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Abstract

OBJECTIVE: To investigate the chemical constituents of the aerial parts of Ribes diacanthum Pall. METHODS: The compounds were isolated and purified by silica gel, Sephadex LH-20 colunm chromatography and HPLC. The structures were elucidated on the basis of spectral data and physiochemical properties. RESULTS: Nineteen compounds were isolated from 95% ethanol extracts and identified as quercetin (1), quercetin-3-O-β-D-glucopyranoside (2), quercetin-3-O-α-L-rhamnopyranoside (3), quercetin-3-O-β-D-neohesperoside (4), mearnsetin (5), myricetin-3-O-α-L-rhamnoside (6), myricetin-3-O-β-D-glucopyranoside (7), mearnsetin 3-O-β-D-glucopyranoside (8), mearnsetin 3-O-α-L-rhamnopyranoside (9), kaempferol-3-O-β-D-glucopyranoside (10), kaempferol 3-O-β-D-(2-O-α-L-rhamnopyranosyl) glucopyranoside (11), kaempferol 3-(2'', 6''-di-O-α-L-rhamnosyl)-β-D-glucoside (12), 1, 2, 4-trihydroxybenzene (13), vanillic acid (14), protocatechuic acid (15), 4-hydroxy benzoic acid (16), gallic acid (17), blumenol C glucoside (18), conocarpan (19). CONCLUSION: All the compounds are isolated from the title plant and the NMR data for 8 is reported here for the first time.

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What this paper is about

OBJECTIVE: To investigate the chemical constituents of the aerial parts of Ribes diacanthum Pall. METHODS: The compounds were isolated and purified by silica gel, Sephadex LH-20 colunm chromatography and HPLC. The structures were elucidated on the basis of spectral data and physiochemical properties. RESULTS: Nineteen compounds were isolated from 95% ethanol extracts and identified as quercetin (1), quercetin-3-O-β-D-glucopyranoside (2), quercetin-3-O-α-L-rhamnopyranoside (3), quercetin-3-O-β-D-neohesperoside (4), mearnsetin (5), myricetin-3-O-α-L-rhamnoside (6), myricetin-3-O-β-D-glucopyranoside (7), mearnsetin 3-O-β-D-glucopyranoside (8), mearnsetin 3-O-α-L-rhamnopyranoside (9), kaempferol-3-O-β-D-glucopyranoside (10), kaempferol 3-O-β-D-(2-O-α-L-rhamnopyranosyl) glucopyranoside (11), kaempferol 3-(2'', 6''-di-O-α-L-rhamnosyl)-β-D-glucoside (12), 1, 2, 4-trihydroxybenzene (13), vanillic acid (14), protocatechuic acid (15), 4-hydroxy benzoic acid (16), gallic acid (17), blumenol C glucoside (18), conocarpan (19). CONCLUSION: All the compounds are isolated from the title plant and the NMR data for 8 is reported here for the first time.

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Available abstract

OBJECTIVE: To investigate the chemical constituents of the aerial parts of Ribes diacanthum Pall. METHODS: The compounds were isolated and purified by silica gel, Sephadex LH-20 colunm chromatography and HPLC. The structures were elucidated on the basis of spectral data and physiochemical properties. RESULTS: Nineteen compounds were isolated from 95% ethanol extracts and identified as quercetin (1), quercetin-3-O-β-D-glucopyranoside (2), quercetin-3-O-α-L-rhamnopyranoside (3), quercetin-3-O-β-D-neohesperoside (4), mearnsetin (5), myricetin-3-O-α-L-rhamnoside (6), myricetin-3-O-β-D-glucopyranoside (7), mearnsetin 3-O-β-D-glucopyranoside (8), mearnsetin 3-O-α-L-rhamnopyranoside (9), kaempferol-3-O-β-D-glucopyranoside (10), kaempferol 3-O-β-D-(2-O-α-L-rhamnopyranosyl) glucopyranoside (11), kaempferol 3-(2'', 6''-di-O-α-L-rhamnosyl)-β-D-glucoside (12), 1, 2, 4-trihydroxybenzene (13), vanillic acid (14), protocatechuic acid (15), 4-hydroxy benzoic acid (16), gallic acid (17), blumenol C glucoside (18), conocarpan (19). CONCLUSION: All the compounds are isolated from the title plant and the NMR data for 8 is reported here for the first time.

Key concepts: Vanillic acid, Myricetin, Quercetin, Kaempferol, Protocatechuic acid, Ribes, Chemistry, Gallic acid

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