Effects of Shuxuetong on diabetic nephropathy in elderly patients

Objective To observe the clinical effects of western medicine combined with Shuxuetong on elderly patients with diabetic nephropathy(DN),and to investigate the effects on hemorheology.Methods Thirty-nine patients with diabetes were divided into two groups,treatment group(19 cases)and control group(20 cases).The clinical effects,blood hemorheology parameters,urinary protein and renal function changes between two groups were compared.Results The symptoms in both groups were significantly improved,but the total effective rate in treatment group was significantly better than that in control group(84.2% vs 35%).In treatment group,there was a significant difference in whole blood viscosity(high-cut,medium-cut,low-cut),fibrinogen,plasma viscosity and erythrocyte sedimentation rate(P0.05) between before and after treatment.Compared with the control group,the whole blood viscosity,fibrinogen,plasma viscosity and erythrocyte sedimentation rate were significantly improved after treatment(P0.05).The levels of blood urea nitrogen and creatinine were significantly improved in two groups after treatment(P0.05).Compared to control group,the level of urinary protein was significantly decreased in treatment group(P0.01).Conclusions Western medicine combined with Shuxuetong treatment could effectively improve the clinical symptoms of elderly patients with DN.