Effect of Liuwei Dihuang Pills on peripheral blood IgE and CD23 in children with primary nephrotic syndrome and efficacy observation

Objective To observe the changes of peripheral serum IgE and CD23 levels and short clinical efficacy after the treatment of Liuwei Dihuang Pills in children patients with primary nephrotic syndrome.Methods 60 children patients with primary nephrotic syndrome were selected and randomly divided into the control group and the observation group,30 cases in each group.The control group was given the conventional treatment,while on this basis the observation group was given Liuwei Dihuang Pills.The treatment lasted for 6weeks.The short term clinical efficacy and the changes of peripheral serum IgE and CD23 levels were observed.Results The short term clinical efficacy after treatment in the observation group was significantly better than that in the control group(P0.05);the levels of peripheral serum TC,TG,SCr,BUN and IgE,CD23 after treatment in the two groups were decreased compared with those before treatment(P0.05);the levels of peripheral serum TC,TG,SCr,BUN and IgE,CD23 after treatment in the observation group were lower than those in the control group(P0.05).Conclusion Giving Liuwei Dihuang Pills on the basis of basic treatment can better improve the short term clinical effect.The comprehensive,careful and normative nursing care during the treatment process is the foundation of the treatment success.