The Clinical Study of Thinprep Cytology Test in Screening Cervical Cancer

Objective:To analyse the female cervical diseases and comprehensively evaluate the application of Thinprep cytology test(TCT)and Bethesdas cytological system(TBS)in screening of cervical cancer.Method:TCT were conducted in 2600 out-patients of gynecology in our hospital,and the results were analysed by Betheda diagnostic criteria.The patients were divided into 6 groups according to ages for observation and comparison.And they were followed up for 6-18 months.Results:409 cases with abnormal squamous epithelium (15.73%) included 167 cases with ASCUS(atipical spuamous cells of undertermined significance),2 cases with AGUS(atipical glandular cells of undertermined significance),210 cases with LSIL(low-grade squamous intraepithelial lesion),28 cases with HSIL(high-grade squamous intraepithelial lesion)and 2 cases with SCC(squamous carcinoma).Biopsy was conducted in 205 cases with abnormal epithelium.Cytology test detected SIL in 114 cases with the detecting rate of 4.38%.Histopathological test detected CIN in 117 cases with the detecting rate of 3.73%.The coincident rate of the diagnosis of TCT cytology and histology was 89.21%.Conclusion:The age of cervical diseases tends to be younger.TCT applying in screening cervical cancer can elevate the detecting rate of cervical abnormal cells.TBS is direct and concrete,facilitating the communication between the clinical doctors and cytologist.The patients with atypical epithelial cells should be observed for 4 to 6 months or conducted biopsy under colposcopy.