2007•Chinese Journal of Modern Drug ApplicationRequires access

Treating genitourinary infections with levofloxacin by continuous intravenous drip or sequential therapy:pharmacoeconomic analysis

Zhong Yuan-hu

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Abstract

Objective To evaluate the pharmacoeconomic outcome of 2 therapeutic schemes of levofloxacin in treatment of genitourinary infections.Methods 83 patients with genitourinary infections were randomly divided into group A and group B.44 cases in group A were assigned to receive levofloxacin injection by continuous intravenous drip,another 39 cases in group B to receive levofloxacin injection/capsule by sequential therapy.The pharmacoeconomic analysis was performed on the 2 groups.Results No significant difference noted between 2 groups in effective rates,bacterial clearance rates,and incidences of ADRS(P0.05),but the treatment cost in group A was significantly higher than in group B(P0.05).Conclusion The sequential therapy with levofloxacin for genitourinary infections is preferable.

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Objective To evaluate the pharmacoeconomic outcome of 2 therapeutic schemes of levofloxacin in treatment of genitourinary infections.Methods 83 patients with genitourinary infections were randomly divided into group A and group B.44 cases in group A were assigned to receive levofloxacin injection by continuous intravenous drip,another 39 cases in group B to receive levofloxacin injection/capsule by sequential therapy.The pharmacoeconomic analysis was performed on the 2 groups.Results No significant difference noted between 2 groups in effective rates,bacterial clearance rates,and incidences of ADRS(P0.05),but the treatment cost in group A was significantly higher than in group B(P0.05).Conclusion The sequential therapy with levofloxacin for genitourinary infections is preferable.

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Available abstract

Objective To evaluate the pharmacoeconomic outcome of 2 therapeutic schemes of levofloxacin in treatment of genitourinary infections.Methods 83 patients with genitourinary infections were randomly divided into group A and group B.44 cases in group A were assigned to receive levofloxacin injection by continuous intravenous drip,another 39 cases in group B to receive levofloxacin injection/capsule by sequential therapy.The pharmacoeconomic analysis was performed on the 2 groups.Results No significant difference noted between 2 groups in effective rates,bacterial clearance rates,and incidences of ADRS(P0.05),but the treatment cost in group A was significantly higher than in group B(P0.05).Conclusion The sequential therapy with levofloxacin for genitourinary infections is preferable.

Key concepts: Levofloxacin, Medicine, Genitourinary system, Group B, Surgery, Internal medicine, Antibiotics, Biology

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