Cost-effectiveness of Sequntial Therapy of Levofloxacin in Subaspiratory Bacterial Infection

OBJECTIVE:To evaluate pharmacoeconomic effect of sequntial therapy of levofloxacin on subaspiratory bacterial infection. METHODS: 180 cases with subaspiratory bacterial infection were randomly divided into group A and group B, 90 patients were in each group. Levofloxacin was given by continuous intravenous infusion in group A, and both levofloxacin injection and tablets by sequntial therapy were given in group B. Two schemes were analyzed by minimal cost analysis of pharmacoeconomics. RESULTS:There was no significant difference ( P 0.05) among clinical curative effect, adverse-effect and germ-clearance, but the expenses in group A were higher than that in group B ( P 0.01). CONCLUSION:It is safe, effective,economic and rational for the patients with subaspiratory bacterial infection by sequntial therapy of levofloxacin injection with levofloxacin tablets.