Comparison of patient-controlled analgesia with tramadol versus flurbiprofen axetil in patients undergoing intestinectomy

Objective To assess the analgesic efficacy and safety of patient-controlled analgesia with tramadol or flurbiprofen axetil in patients undergoing intestinectomy. Methods 50 patients scheduled for intestinectomy under general anesthesia were randomly allocated to flurbiprofen axetil (Group F) and tramadol (Group T) for postoperative patient-controlled analgesia(PCA). Efficacy was assessed by a 5-point verbal rating scores of pain intensity. Possible adverse events were also recorded. Results Statistical analysis revealed no significant difference in a 5-point verbal rating scores of pain intensity between flurbiprofen axetil and tramadol. Flurbiprofen axetil caused fewer side effects such as dizziness,nausea and vomiting than tramadol. Conclusion Flurbiprofen axetil offered a useful alternative to tramadol with less side effects for the patient-controlled analgesia of postoperative pain.