Comparison of postoperative analgesia with flurbiprofen axetil versus tramadol in patients undergoing laparoscopically hysterectomy

Objective:To assess the efficacy and safety of persistent analgesia with flurbiprofen axetil versus tramadol in patients undergoing laparoscopically hysterectomy.Methods: 40 patients undergoing laparoscopically hysterectomy were randomly administered with one of two intravenous anesthesics: flurbiprofen axetil(50mg,n=20) or tramadol(100mg,n=20) 30 minutes prior to the termination of the surgery.Both groups received postoperative PCA(0.5mL each time,2mL·h-1) as analgesia.The efficacy was assessed based on pain scores(BCS) and the safety was evaluated based on the incidence of adverse events.Results: No significant difference of pain scores(BCS) and incidence of AEs between both treatment groups was found.Conclusion: Flurbiprofen axetil offers an alternative option for the patient-controlled analgesia of postoperative pain.