STUDY ON THE FACTORS INFLUENCING EFFICACY OF EOW IN KILLING Candida albicans

Objective To study the factors influencing efficacy of electrolyzed oxidizing water(EOW) in killing Candida albicans.Methods Suspension quantitative germicidal test method was used to observe the factors influencing efficacy of EOW in killing C.Albicans.Results In clean condition,the EOW containing available chlorine concentration(ACC) 53.7 mg/L with a contact time more than 3 min,or ACC ≥65.5 mg/L with a contact time 1 min killed C.albicans by a killing logarithm(KL) higher than 4.67.If organic interfering substance was added,the EOW containing ACC 65.5 mg/L with a 1 min contact time killed C.albicans in suspension containing 3 g/L organic substance by KL value 1.31 and KL value 0.22 in suspension containing 30 g/L organic substance.The germicidal efficacy of EOW dropped with increasing pH and decreasing oxidation reduction potential(ORP).With high ACC,the germicidal efficacy of EOW was less affected by the change of pH while pH≤8 and KL was approximate 5.86.Conclusions EOW has good efficacy in killing C.albicans,and the efficacy improved with increasing ACC.Interfering substance has strong suppressive effect on germicidal efficacy of EOW.The germicidal efficacy of EOW in acidic condition is higher than that in alkaline condition.Thus a conclusion is deduced that the germicidal efficacy of EOW is decided by a synergistic effect of three factors: leading by ACC,low pH and high ORP.