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2001•Journal of Nantong MedicalRequires access

THE IMMUNOHISTOCHEMICAL STUDY OF GAP-43 EXPRESSION IN LESIONED SCIATIC NERVE

Wan Heming

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Abstract

Objective:To study the expression of Growth -Associated-Protein-43(GAP-43) in the distal stump of rat sciatic nerve defect.Methods:Two weeks after rat sciatic nerve injury ,we investigated the expression of GAP-43 in the distal stump and normal nerve with immunohistochemical staining.Results: Positive reactions of GAP-43 were found on the surface of Schwann cell in distal stump while there is no expression in normal sciatic nerve. Conclution:GAP-43 localizes in the Schwann cell in distal stump after sciatic nerve injury ,but it can not be found in normal nerve.

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What this paper is about

Objective:To study the expression of Growth -Associated-Protein-43(GAP-43) in the distal stump of rat sciatic nerve defect.Methods:Two weeks after rat sciatic nerve injury ,we investigated the expression of GAP-43 in the distal stump and normal nerve with immunohistochemical staining.Results: Positive reactions of GAP-43 were found on the surface of Schwann cell in distal stump while there is no expression in normal sciatic nerve. Conclution:GAP-43 localizes in the Schwann cell in distal stump after sciatic nerve injury ,but it can not be found in normal nerve.

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Available abstract

Objective:To study the expression of Growth -Associated-Protein-43(GAP-43) in the distal stump of rat sciatic nerve defect.Methods:Two weeks after rat sciatic nerve injury ,we investigated the expression of GAP-43 in the distal stump and normal nerve with immunohistochemical staining.Results: Positive reactions of GAP-43 were found on the surface of Schwann cell in distal stump while there is no expression in normal sciatic nerve. Conclution:GAP-43 localizes in the Schwann cell in distal stump after sciatic nerve injury ,but it can not be found in normal nerve.

Key concepts: Sciatic nerve, Immunohistochemistry, Schwann cell, Sciatic nerve injury, Anatomy, Cell bodies, Pathology, Medicine

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