2013•Journal of medical imagingRequires access

Solitary fibrous tumors:imaging diagnosis and clinical pathological correlation

Wei Xiong

Open publisher page 0 citations

Abstract

Objective We aimed to analyze the computed tomography(CT),magnetic resonce imaging(MRI)and pathological findings of solitary fibrous tumors(SFT).Methods CT,MRI and pathology images of 23 patients with SFT confirmed by pathology were retrospecively reviewed,and a comparison with histopathological and immunohistochemical results were made.Results 20 cases showed solitary oval or rouned well-defined masses,and 3 cases showed cystic solid masses.Contrast-enhanced images showed marked,heterogeneous enhancement,and delayed enhancement.On T1WI and T2WI,most tumors were hypointensive.The pathological features of SFT contained mixed various amount of spindle cells and collagen,with CD34 and Vimentin being immunohistochemical positivity.Four cases of malignant solitary fibrous tumors demonstrated cytological atypia obviously and tumor necrosis.Conclusion SFT can be seen in multi-parts of the body,and can demonstrate characteristic CT and MRI features,which is helpful for the diagnosis,yet final diagnosis should be based on histopathology and immunohistochemistry examinations.

About this research paper

What this paper is about

Objective We aimed to analyze the computed tomography(CT),magnetic resonce imaging(MRI)and pathological findings of solitary fibrous tumors(SFT).Methods CT,MRI and pathology images of 23 patients with SFT confirmed by pathology were retrospecively reviewed,and a comparison with histopathological and immunohistochemical results were made.Results 20 cases showed solitary oval or rouned well-defined masses,and 3 cases showed cystic solid masses.Contrast-enhanced images showed marked,heterogeneous enhancement,and delayed enhancement.On T1WI and T2WI,most tumors were hypointensive.The pathological features of SFT contained mixed various amount of spindle cells and collagen,with CD34 and Vimentin being immunohistochemical positivity.Four cases of malignant solitary fibrous tumors demonstrated cytological atypia obviously and tumor necrosis.Conclusion SFT can be seen in multi-parts of the body,and can demonstrate characteristic CT and MRI features,which is helpful for the diagnosis,yet final diagnosis should be based on histopathology and immunohistochemistry examinations.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective We aimed to analyze the computed tomography(CT),magnetic resonce imaging(MRI)and pathological findings of solitary fibrous tumors(SFT).Methods CT,MRI and pathology images of 23 patients with SFT confirmed by pathology were retrospecively reviewed,and a comparison with histopathological and immunohistochemical results were made.Results 20 cases showed solitary oval or rouned well-defined masses,and 3 cases showed cystic solid masses.Contrast-enhanced images showed marked,heterogeneous enhancement,and delayed enhancement.On T1WI and T2WI,most tumors were hypointensive.The pathological features of SFT contained mixed various amount of spindle cells and collagen,with CD34 and Vimentin being immunohistochemical positivity.Four cases of malignant solitary fibrous tumors demonstrated cytological atypia obviously and tumor necrosis.Conclusion SFT can be seen in multi-parts of the body,and can demonstrate characteristic CT and MRI features,which is helpful for the diagnosis,yet final diagnosis should be based on histopathology and immunohistochemistry examinations.

Key concepts: Medicine, Solitary fibrous tumor, Histopathology, Pathological, Immunohistochemistry, Pathology, CD34, Vimentin

Related papers

Back to paper searchBrowse research topicsOriginal source
Solitary fibrous tumors:imaging diagnosis and clinical pathological correlation — Research Paper | ScholarLens