Solitary fibrous tumors:imaging diagnosis and clinical pathological correlation
Wei Xiong
Abstract
Wei Xiong
Abstract
Objective We aimed to analyze the computed tomography(CT),magnetic resonce imaging(MRI)and pathological findings of solitary fibrous tumors(SFT).Methods CT,MRI and pathology images of 23 patients with SFT confirmed by pathology were retrospecively reviewed,and a comparison with histopathological and immunohistochemical results were made.Results 20 cases showed solitary oval or rouned well-defined masses,and 3 cases showed cystic solid masses.Contrast-enhanced images showed marked,heterogeneous enhancement,and delayed enhancement.On T1WI and T2WI,most tumors were hypointensive.The pathological features of SFT contained mixed various amount of spindle cells and collagen,with CD34 and Vimentin being immunohistochemical positivity.Four cases of malignant solitary fibrous tumors demonstrated cytological atypia obviously and tumor necrosis.Conclusion SFT can be seen in multi-parts of the body,and can demonstrate characteristic CT and MRI features,which is helpful for the diagnosis,yet final diagnosis should be based on histopathology and immunohistochemistry examinations.
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Objective We aimed to analyze the computed tomography(CT),magnetic resonce imaging(MRI)and pathological findings of solitary fibrous tumors(SFT).Methods CT,MRI and pathology images of 23 patients with SFT confirmed by pathology were retrospecively reviewed,and a comparison with histopathological and immunohistochemical results were made.Results 20 cases showed solitary oval or rouned well-defined masses,and 3 cases showed cystic solid masses.Contrast-enhanced images showed marked,heterogeneous enhancement,and delayed enhancement.On T1WI and T2WI,most tumors were hypointensive.The pathological features of SFT contained mixed various amount of spindle cells and collagen,with CD34 and Vimentin being immunohistochemical positivity.Four cases of malignant solitary fibrous tumors demonstrated cytological atypia obviously and tumor necrosis.Conclusion SFT can be seen in multi-parts of the body,and can demonstrate characteristic CT and MRI features,which is helpful for the diagnosis,yet final diagnosis should be based on histopathology and immunohistochemistry examinations.
Key concepts: Medicine, Solitary fibrous tumor, Histopathology, Pathological, Immunohistochemistry, Pathology, CD34, Vimentin