2007•Acta Academiae Medicinae JiangxiRequires access

Imaging Diagnosis and Pathological Analysis of Solitary Fibrous Tumors

Chen Fu-jiana

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Abstract

Objective To study the pathological and imaging features of the solitary fibrous tumors(SFT)and improve the diagnosis of the SFT.Methods 8 patients with SFT who were confirmed by reviewing patients surgical and pathology records were retrospectively analyzed and a comparison with histopathological and immunohistochemical results was made.Results(1)A smooth margined solitary mass was founded in the lung in two cases,in the cavity of pelvis in two cases,in the cervical part in two cases,in the retroperitoneal phyma and in the maxillary sinus in one case.(2)On CT scans,cystic degeneration area and marked enhancement of tumor's parenchyma were demonstrated.(3)On T2WI,most tumors were hypointense,and larger lesions displayed low-high mixed signal with signal void of flow.(4)Microscopically,SFTwas composed of spindle cells arranged in different patterns,with CD 34,CD99 being immunohistochemical positive.Conclusion SFT is a soft tissue tumor originated from mesenchyma.The possibility of SFT should be considered when a soft tissue mass with sharp border,marked enhancement of tumor's parenchyma and on T1WI intermediate or hypointensed while on T2WI hypointensed tumor is seen on imaging examination.However,the verification of the diagnosis should be based on the histopathological and immunohistochemical examinations.

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Objective To study the pathological and imaging features of the solitary fibrous tumors(SFT)and improve the diagnosis of the SFT.Methods 8 patients with SFT who were confirmed by reviewing patients surgical and pathology records were retrospectively analyzed and a comparison with histopathological and immunohistochemical results was made.Results(1)A smooth margined solitary mass was founded in the lung in two cases,in the cavity of pelvis in two cases,in the cervical part in two cases,in the retroperitoneal phyma and in the maxillary sinus in one case.(2)On CT scans,cystic degeneration area and marked enhancement of tumor's parenchyma were demonstrated.(3)On T2WI,most tumors were hypointense,and larger lesions displayed low-high mixed signal with signal void of flow.(4)Microscopically,SFTwas composed of spindle cells arranged in different patterns,with CD 34,CD99 being immunohistochemical positive.Conclusion SFT is a soft tissue tumor originated from mesenchyma.The possibility of SFT should be considered when a soft tissue mass with sharp border,marked enhancement of tumor's parenchyma and on T1WI intermediate or hypointensed while on T2WI hypointensed tumor is seen on imaging examination.However,the verification of the diagnosis should be based on the histopathological and immunohistochemical examinations.

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Available abstract

Objective To study the pathological and imaging features of the solitary fibrous tumors(SFT)and improve the diagnosis of the SFT.Methods 8 patients with SFT who were confirmed by reviewing patients surgical and pathology records were retrospectively analyzed and a comparison with histopathological and immunohistochemical results was made.Results(1)A smooth margined solitary mass was founded in the lung in two cases,in the cavity of pelvis in two cases,in the cervical part in two cases,in the retroperitoneal phyma and in the maxillary sinus in one case.(2)On CT scans,cystic degeneration area and marked enhancement of tumor's parenchyma were demonstrated.(3)On T2WI,most tumors were hypointense,and larger lesions displayed low-high mixed signal with signal void of flow.(4)Microscopically,SFTwas composed of spindle cells arranged in different patterns,with CD 34,CD99 being immunohistochemical positive.Conclusion SFT is a soft tissue tumor originated from mesenchyma.The possibility of SFT should be considered when a soft tissue mass with sharp border,marked enhancement of tumor's parenchyma and on T1WI intermediate or hypointensed while on T2WI hypointensed tumor is seen on imaging examination.However,the verification of the diagnosis should be based on the histopathological and immunohistochemical examinations.

Key concepts: Solitary fibrous tumor, Pathological, Soft tissue, Immunohistochemistry, Pathology, Medicine, Pelvis, CD99

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