Study on the mutagenic breeding of the strain of Streptomyces natalensis by electrofusion impulse

Using the electrofusion impulse as mutagenic agent to treatment Streptomyces natalensis and with added streptomycin sulfate plat creening resist strains,a high-natamycin mutant strain SN114 was obtained.At the same fermentation conditions,that the yield of natamycin was 1.098g/L and 1.6 times of that of original strain's.The mutual strain has a good genetic stability of descendiblity of natamyin production after being inoculated for five subsequent generations.