Effects of bFGF Complex Non-Degradated Membrane on Allogenic Nerve Transplantation: a Morphological Study

Objective To explore the effects of bFGF complex non degradated membrane on the transplantation of allogenic nerve. Method 18 New Zerland Rabbits are randomly classified into A and B groups total 36 medial nerves. A group is bridged by medial nerves 3 cm with recipient plasma cryopreservation, the B group is grafted by that only with cryopreservation. The transplanted site of the left limb are coated by the bFGF complex non degratated membrane. Observation and analysis were made histologically and quantitatively 180 days after intervention. Results The number of regenerating nerve fibers of the left limb is more than that in the right, collagenous fibers of connective tissue among nerve fibers of the left limb are less than those of the right. The number of nerve regeneration of the left limb in A group is more than that in B group. Conclusions ① bFGF complex non degradation pellicle and decreasing Vitamin C are effective in improving nerve regeneration. ② Nerve allografters with recipient plasma cryopreservation could get a better nerve regeneration and a lesser connective tissue proliferation.