ScholarLens Back to search
2010•Chinese Journal of ArteriosclerosisRequires access

The Effect of Edaravone on Serum NO,NOS,MDA and SOD in Patients with Acute Cerebral Infarction

Bin Li

Open publisher page 1 citations

Abstract

Aim To observe the effect of edaravone on serum NO,NOS and SOD in patients with cerebral infarction. Methods 160 cases with cerebral infarction were randomly divided into edaravone treatment group(treatment group) and conventional treatment group(control group),80 cases in each group.NO,NOS,MDA and SOD were measured before and after treatment for 7 d and 14 d. Results Control group's NO,NOS and MDA had no obvious change before and after treatment.The results after treated for 7 d were lower than before treatment,but higher than after treated for 14 d.Treatment group's NO,NOS and MDA were lower than control group's(P0.05).Treatment group's SOD was gradually increased and obviously higher than control group's(P0.05). Conclusion Edaravone has certain protective effect on cerebral infarction patients by decreasing their serum NO,NOS and MDA and increasing SOD activity.

About this research paper

What this paper is about

Aim To observe the effect of edaravone on serum NO,NOS and SOD in patients with cerebral infarction. Methods 160 cases with cerebral infarction were randomly divided into edaravone treatment group(treatment group) and conventional treatment group(control group),80 cases in each group.NO,NOS,MDA and SOD were measured before and after treatment for 7 d and 14 d. Results Control group's NO,NOS and MDA had no obvious change before and after treatment.The results after treated for 7 d were lower than before treatment,but higher than after treated for 14 d.Treatment group's NO,NOS and MDA were lower than control group's(P0.05).Treatment group's SOD was gradually increased and obviously higher than control group's(P0.05). Conclusion Edaravone has certain protective effect on cerebral infarction patients by decreasing their serum NO,NOS and MDA and increasing SOD activity.

Why it matters

OpenAlex reports 1 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Aim To observe the effect of edaravone on serum NO,NOS and SOD in patients with cerebral infarction. Methods 160 cases with cerebral infarction were randomly divided into edaravone treatment group(treatment group) and conventional treatment group(control group),80 cases in each group.NO,NOS,MDA and SOD were measured before and after treatment for 7 d and 14 d. Results Control group's NO,NOS and MDA had no obvious change before and after treatment.The results after treated for 7 d were lower than before treatment,but higher than after treated for 14 d.Treatment group's NO,NOS and MDA were lower than control group's(P0.05).Treatment group's SOD was gradually increased and obviously higher than control group's(P0.05). Conclusion Edaravone has certain protective effect on cerebral infarction patients by decreasing their serum NO,NOS and MDA and increasing SOD activity.

Key concepts: Edaravone, Medicine, Cerebral infarction, Internal medicine, Gastroenterology, Free radical scavenger, Infarction, Anesthesia

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
The Effect of Edaravone on Serum NO,NOS,MDA and SOD in Patients with Acute Cerebral Infarction — Research Paper | ScholarLens